Table 2.
Impact of DIA on the parameters of hepatic oxidative stress in rats treated with APAP
| Parameters | Control | APAP | DIA 25 + APAP | DIA 50 + APAP |
|---|---|---|---|---|
| MDA (nmol/g. tissue) | 0.41 ± 0.31 | 3.56 ± 0.18a | 1.22 ± 0.08a,b | 0.78 ± 0.01b,c |
| GSH (mmol/g. tissue) | 101.40 ± 0.43 | 64.99 ± 1.16a | 85.82 ± 1.12a,b | 97.31 ± 0.62a,b,c |
| GPx (U/g. tissue) | 152.90 ± 1.10 | 103.10 ± 0.77a | 141.30 ± 1.03a,b | 148.5 ± 0.43a,b,c |
| SOD (U/g. tissue) | 162.60 ± 1.10 | 95.90 ± 0.70a | 137.5 ± 0.91a,b | 152.1 ± 0.90a,b,c |
| CAT (U/g. tissue) | 199.80 ± 2.60 | 105.30 ± 1.50a | 139.10 ± 0.80a,b | 160 .40 ± 1.00a,b,c |
Data were expressed in the form of means ± S.E.M. (n = 6 per group), and then data analysis was performed utilizing the one-way ANOVA and then the Tukey post hoc test. (a), (b), (c): P < 0.05, compared to controls, APAP, DIA 25 + APAP groups, respectively