Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 1;13:1731. doi: 10.1038/s41467-022-29420-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — a Scaled abundance of hypoxia proteins with a downregulation trend (GSEA gene list MANALO_HYPOXIA_DOWN) by proteome analysis in HCT116 and BRG1 knockout (KO) cells at early time points. Duplicates are represented as R1 and R2. b Scaled abundance of hypoxia proteins with upregulation trend (GSEA gene list MANALO_HYPOXIA_UP) by proteome analysis in HCT116 and BRG1 KO cells at early time points. Duplicates are represented as R1 and R2. c Heatmap showing a scaled abundance of glycolysis proteins in HCT116 and BRG1 KO cells at early time points. Duplicates are shown side by side. The colour key indicates the relative abundance of each protein (scale: 0–160). d Scaled abundance of SLC2A1 and SLC2A3 glucose importers by proteome analysis in HCT116 and BRG1-deficient cells at early time points. Data were presented as the mean; n = 2. e Heatmap showing scaled abundance of proteasome proteins in HCT116 and BRG1-deficient (KO) cells at early, mid and late time points. Duplicates are shown side by side. The colour key indicates the relative abundance of each protein (scale: 0–150). f Scaled abundance of immunoproteasome subunits by proteome analysis in HCT116 and BRG1-deficient (KO) cells at early time points. Data were presented as the mean; n = 2. g mRNA expression of immunoproteasome subunits in HCT116 and two BRG1-deficient (KO) clones by RT-PCR analysis. The values have been normalised to GAPDH expression. Data were presented as the mean ± SD; n = 5. The p value was calculated with two-way ANOVA-Dunnett. *p < 0.05, **p < 0.01 and ***p < 0.001.