Table 2.

Differentially Expressed Barrier Genes and miRNAs Implicated as Regulators of These Genes

	Expression, CPMa
Gene	Control	FD	Fold Change	FDR	Regulatory miRNAs	Fold Change	P Value
ZO-1	82.7, 157.9	95.4, 135.8	0.87	0.02	hsa-miR-369-3p	1.085	7.88e-25
					hsa-miR-144-3p	1.163	.002
					hsa-miR-374a-5p	1.36	3.18e-60
OCLN	75.1, 146.3	75, 122.7	0.81	0.003	hsa-miR-590-3p	1.366	4.19e-26
CLDN-12	38.9, 71.9	37.8, 50.8	0.77	0.00003	hsa-miR-142-3p	2	2.33e-22
					hsa-let-7a-3p	1.005	7.89e-33
					hsa-miR-369-3p	1.085	7.88e-25
					hsa-miR-144-5p	1.91	.0000003
E-cadherin	513.9, 781.3	541.8, 765	0.9	0.04	hsa-miR-9-5p	0.5	1.26e-19
β-catenin	403.1, 600.1	456.4, 616.6	0.93	0.3	hsa-let-7a-3p	1.005	7.89e-33
p120 catenin	417.7, 597.7	464.4, 609.8	0.93	0.009	hsa-miR-30c-2-3p	0.45	6.26e-41
DSG-2	300.4, 495	283.9, 461.4	0.8	0.0004	hsa-miR-374a-5p	1.357	3.18e-60
					hsa-let-7a-3p	1.005	7.89e-33
					hsa-miR-590-3p	1.366	4.19e-26
DSC-2	245, 520.9	237.2, 459.8	0.8	0.006	hsa-miR-32-5p	1.13	4.13e-44
					hsa-miR-4521	1.16	8.93e-09

CPM, counts per million; FDR, false discovery rate; miRNAs, microRNAs; FD, functional dyspepsia.

^a5th percentile, 95th percentile.