Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 1;12:5508. doi: 10.1038/s41598-022-09421-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Genotype combinations predictive of anxiety symptoms in males. (A,B) Average anxiety scores for males with a combination of PER3B-AG and CRY1-CG are higher than average anxiety scores of individuals with other genotype combinations (Gender: F_{1, 479} = 0.661, p = 0.417, Genotype: F_{1, 479} = 7.174, p = 0.008; Gender x Genotype: F_{1, 479} = 4.141, p = 0.042). Anxiety scores are measured using the self-reported State-Trait Anxiety Index (± 1 SE). Tukey’s posthoc tests showed that males with AC-CG combination were significantly different from males with other genotypes and from females. (C,D) Average anxiety scores of males with a combination of CLOCK3111-TC and CRY2-AG also tend to be higher than average anxiety scores of individuals with other genotype combinations, but this is not significant at p < 0.05. (Gender: F_{1, 517} = 1.773; p = 0.184 , Genotype:F_{1, 517} = 3.417; p = 0.065; Gender x Genotype: F_{1, 517} = 1.912, p = 0.167).