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. 2022 Apr 1;8:35. doi: 10.1038/s41531-022-00288-w

Table 2.

Performance metric summaries comparing training in withheld samples in PPMI.

Data Modality Genetics (P < 1E-5) Clinico-demographic Transcriptomics (P < 1E-2) Combined
Stage Training in PPMI (70:30) Training in PPMI (70:30) Training in PPMI (70:30) Training in PPMI (70:30)
Algorithm MLPClassifier LogisticRegression SVC AdaBoostClassifier
AUC (%) 70.66 87.52 79.73 89.72
Accuracy (%) 70.00 79.44 73.89 85.56
Balanced accuracy (%) 60.64 75.27 54.60 82.41
Log Loss 0.83 0.39 0.48 0.63
Sensitivity 0.83 0.85 0.97 0.89
Specificity 0.38 0.65 0.12 0.76
PPV 0.77 0.86 0.75 0.91
NPV 0.48 0.64 0.60 0.73