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Susceptibility to doxycycline and minocycline of A. actinomycetemcomitans ATCC 29522 cultivated under either poor or rich iron conditions
| Antibiotic and iron source (μM) | MIC (μg/ml)
|
|
|---|---|---|
| Assay 1 | Assay 2 | |
| Doxycycline | ||
| FeSO4 | ||
| 1 | 0.094 | 0.094 |
| 5 | 0.25 | 0.125 |
| 50 | 0.50 | 0.38 |
| FeCl3 | ||
| 1 | 0.032 | 0.032 |
| 5 | 0.25 | 0.125 |
| 50 | 0.75 | 0.38 |
| Minocycline | ||
| FeSO4 | ||
| 1 | 0.032 | 0.064 |
| 5 | 0.047 | 0.064 |
| 50 | 0.19 | 0.25 |
| FeCl3 | ||
| 1 | 0.032 | 0.047 |
| 5 | 0.047 | 0.047 |
| 50 | 0.19 | 0.19 |
