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. 2022 Mar 28;15:2051–2073. doi: 10.2147/JIR.S356029

Table 3.

Multiple Regression Analysis of Oxidation, Glycation, and Carbamylation of Salivary and Plasma Proteins, Lipids, and DNA

β1: Age β2: Sex
Estimate 95% CI p-value Estimate 95% CI p-value
Saliva Total thiols level −0.4503 −0.5855 - −0.3151 < 0.0001 −1.344 −8.958–6.27 0.728
Protein carbonyls level 0.02077 0.01454–0.027 < 0.0001 0.06285 −0.2879–0.4136 0.7241
MGO level 0.008252 0.002732–0.01377 0.0036 0.03345 −0.2773–0.3442 0.8321
CML level 0.6253 0.4453–0.8053 < 0.0001 12.34 2.204–22.47 0.0173
AGE level 0.01658 0.01334–0.01982 < 0.0001 0.2036 0.02129–0.3859 0.0288
CBL level 0.01539 0.01067–0.02012 < 0.0001 −0.1421 −0.4083–0.124 0.2934
4-HNE level 0.01584 0.01141–0.02026 < 0.0001 −0.05109 −0.3003–0.1981 0.6863
8-OHdG level 0.02196 0.01783–0.02608 < 0.0001 −0.154 −0.3862–0.07826 0.1924
Plasma Total thiols level −0.1152 −0.1491 - −0.08128 < 0.0001 −0.2048 −2.115–1.706 0.8327
Protein carbonyls level 0.09016 0.0628–0.1175 < 0.0001 −0.08927 −1.63–1.452 0.9091
MGO level 0.09579 0.0738–0.1178 < 0.0001 0.5817 −0.6561–1.82 0.355
CML level 0.9321 0.6263–1.238 < 0.0001 3.591 −13.63–20.81 0.6812
AGE level 0.01235 0.009662–0.01505 < 0.0001 −0.055 −0.2066–0.0966 0.475
CBL level 0.06489 0.04654–0.08325 < 0.0001 −1.139 −2.173 - −0.106 0.0309
4-HNE level 0.03569 0.02855–0.04283 < 0.0001 −0.01329 −0.4153–0.3887 0.948
8-OHdG level 0.02633 0.02141–0.03125 < 0.0001 −0.02482 −0.302–0.2523 0.8599

Abbreviations: AGE, advanced glycation end products; CBL, carbamyl-lysine; CI, confidence interval; CML, Nε-(carboxymethyl) lysine; MGO, methylglyoxal adducts; 4-HNE, 4-hydroxynonenal protein adducts; 8-OHdG, 8-hydroxy-2’-deoxyguanosine.