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. 2021 Oct 29;35(4):337–346. doi: 10.1093/ajh/hpab171

Figure 1.

Figure 1.

Mean mm Hg (95% CI) for (a) systolic blood pressure (SBP) and (b) diastolic blood pressure (DBP) according to randomized intervention throughout the TONE trial: usual care (UC, circle), weight loss (WL, diamond), sodium reduction (SR, triangle), and both weight loss and sodium reduction (Comb, square). Point estimates are shown by study visit: RV (randomization visit), P (visits prior to drug withdrawal), D (drug withdrawal visits, 6-month visits, and 9-month visits), 12–18 (12-, 15-, and 18-month visits), and 21–36 (21-, 24-, 27-, 30-, 33-, and 36-month visits). Point estimates are positioned according to the median follow-time corresponding to each cluster of visits. Number of visits contributing to each point estimate is found in Supplement Table ST3. Note that participants were censored if they experienced the primary outcome (which included high blood pressure). All means are adjusted for obesity status and clinic center. Abbreviations: CI, confidence interval; TONE, Trial of Nonpharmacologic Interventions in the Elderly.