Table 2.

Adverse reaction spectrum of UGT1A1*6 and UGT1A1*28

Adverse reaction	UGT1A1*6		P	UGT1A1*28		P
	WT (n=64)	HM (n=43)		WT (n=81)	HM (n=26)
Vomit grade			0.020			0.013
0	30 (46.88%)	16 (37.21%)		41 (50.62%)	5 (19.23%)
1-2	25 (39.06%)	11 (25.58%)		25 (30.86%)	11 (42.31%)
3-4	9 (14.06%)	16 (37.21%)		15 (18.52%)	10 (38.46%)
Mucositis			0.322			0.005
Yes	46 (71.88%)	27 (62.79%)		61 (75.31%)	12 (46.15%)
No	18 (28.12%)	16 (37.21%)		20 (24.69%)	14 (53.85%)
Diarrhea grade			0.027			0.382
0-2	50 (78.12%)	25 (58.14%)		55 (67.90%)	20 (76.92%)
3-4	14 (21.88%)	18 (41.86%)		26 (32.10%)	6 (23.08%)
Neutropenia grade			0.005			0.241
0-2	43 (67.19%)	17 (39.53%)		48 (59.26%)	12 (46.15%)
3-4	21 (32.81%)	26 (60.47%)		33 (40.74%)	14 (53.85%)
Anemia			0.654			0.820
Yes	53 (82.81%)	37 (86.05%)		69 (85.19%)	21 (80.77%)
No	11 (17.19%)	6 (13.95%)		12 (14.81%)	5 (19.23%)
Thrombocytopenia			0.481			0.510
Yes	54 (84.38%)	34 (79.07%)		65 (80.25%)	23 (88.46%)
No	10 (15.62%)	9 (20.93%)		16 (19.75%)	3 (11.54%)
Fatigue			0.654			0.697
Yes	53 (82.81%)	37 (86.05%)		67 (82.72%)	23 (88.46%)
No	11 (17.19%)	6 (13.95%)		14 (17.28%)	3 (11.54%)