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. 2022 Mar 20;25(3):137–146. doi: 10.3779/j.issn.1009-3419.2022.101.07

Table 3.

Logistic regression of common adverse reactions

Adverse events Gene type B SE Z P OR (95%CI)
*After adjusting the number of treatment lines, treatment plan, smoking, gender, tumor type and hyperbilirubinemia.
*Vomit UGT1A1*6 0.524 0.438 1.198 0.231 1.69 (0.72-3.99)
UGT1A1*28 1.491 0.568 2.623 0.009 4.44 (1.46-13.52)
*Vomit grade UGT1A1*6 1.921 0.573 3.353 0.001 6.83 (2.22-20.98)
UGT1A1*28 1.081 0.577 1.874 0.061 2.95 (0.95-9.14)
*Diarrhea UGT1A1*6 0.128 0.453 0.283 0.777 1.14 (0.47-2.76)
UGT1A1*28 -0.474 0.499 -0.949 0.343 0.62 (0.23-1.66)
*Mucositis UGT1A1*6 0.601 0.447 1.346 0.178 1.82 (0.76-4.38)
UGT1A1*28 1.371 0.484 2.831 0.005 3.94 (1.52-10.17)
*Neutropenia grade UGT1A1*6 1.057 0.459 2.303 0.021 2.88 (1.17-7.08)
UGT1A1*28 0.575 0.506 1.136 0.256 1.78 (0.66-4.79)