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. 2022 Feb 8;37(1):3–12. doi: 10.1093/mutage/geac001

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© The Author(s) 2022. Published by Oxford University Press on behalf of the UK Environmental Mutagen Society.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Characteristics of studies included in this meta-analysis. (A) The number of studies using the CBMN assay since its conception in 1985. (B) Cyt-B concentration used (some studies used more than one concentration). (C) Frequency of radiation type used in different studies. (D) Time between irradiation and cyt-B addition. (E) Time between cyt-B addition and MN fixation. (F) Overall time between irradiation and fixation. Red arrows indicate the timings detailed by the Fenech protocol (44, 24–28, and 68–82 h for D, E, and F, respectively).