Table 2.
Comparation within-groups and differences group-by-time interaction for primary outcomes
|
Baseline Final assessment |
Baseline Follow-up 1 |
Baseline Follow-up 2 |
Baseline Follow-up 3 |
Interaction group*time | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Mean change (95%CI) | p value | Mean change (95%CI) | p value | Mean change (95%CI) | p value | Mean change (95%CI) | p value | F; df; p value | ||
| Primary outcomes | Groups | |||||||||
| Frequency of headachea |
IG SUG |
1.13 (-2.29; 4.57) 1.16 (-2.06; 4.38) |
0.513 0.477 |
1.19 (-2.23; 4.62) 1.01 (-2.21; 4.23) |
0.492 0.536 |
2.07 (-1.35; 5.51) 0.41 (-2.81; 3.63) |
0.233 0.801 |
2.43 (-1.00; 5.86) 0.01 (-3.21; 3.23) |
0.163 0.994 |
0.44; 4; 0.782 |
| Intensity of pain (NRS) |
IG SUG |
2.96 (2.03; 3.90) 3.73 (2.85; 4.62) |
0.001*CR 0.001*CR |
3.31 (2.38;4.25) 2.78 (1.90; 3.67) |
0.001*CR 0.001*CR |
3.96 (3.03; 4.90) 3.53 (2.65; 4.42) |
0.001*CR 0.001*CR |
4.02 (3.08;4.96) 3.38 (2.50; 4.27) |
0.001*CR 0.001*CR |
1.51; 4; 0.202 |
95%CI 95% confidence interval, IG intervention group, SUG sham ultrasound group, NRS numerical rating scale
arepresented in days with headache per month
*p < 0.005
CRclinically relevant