Figure 2.

Retinal signaling in Kv8.2 KO animals. ERG responses following the standard ISCEV protocol were collected from 9 WT (black) and 9 Kv8.2 KO (red) animals ranging in age from 1 to 4 months. Representative traces are shown above quantitation of the amplitude of the b wave as a fraction of the a wave amplitude for (A–D), or the amplitude between the peaks of the first negative and first positive deflection for (E). (A) Scotopic dim flash, (B) Scotopic bright flash, (C) oscillatory potentials extracted from (B), (D) standard combined response (rod plus cone), (E) 30 Hz flicker. Scale is 200 μV (A–C) or 100 μV (D, E) by 40 ms.