Table 2.
Cone response parameters from ex vivo recordings
| R max (μV) | I 1/2 (Photons μm−2) | S fD (Photons−1 μm−2) | t p (ms) | t int (ms) | τ rec (ms) | N | |
|---|---|---|---|---|---|---|---|
| WT | 87 ± 6 | 2649 ± 362 | 5.0 ± 0.7 × 104 | 59 ± 3 | 131 ± 11 | 32 ± 5 | 7 retinas (5 mice) |
| Kv8.2 KO | 70 ± 6 | 4224 ± 637 | 3.0 ± 0.5 × 104 | 57 ± 1 | 91 ± 2 | 15 ± 1 | 10 retinas (6 mice) |
| P-value | 0.051 | 0.0501 | 0.043 | 0.68 | 0.011 | 0.0075 |
R max, saturated response amplitude measured at the plateau; I1/2, intensity required to produce half of the saturated response; SfD, dark-adapted sensitivity; tp, time to peak of a dim flash response; tint, integration time of the response; τrec, recovery time constant during response shut off.