Table 1.
Characteristic | Period (month/year) | p-value | |||
---|---|---|---|---|---|
3/2020 to 2/2022 | 3/2020 to 2/2021 | 3/2021 to 12/2021 | 1/2022 to 2/2022 | ||
Documented COVID-19 episodes | 57 (100.0%) | 28 (49.1%) | 11 (19.3%) | 18 (31.5%) | |
Available COVID-19 episodes for analysis | 53 (93.0%) | 24 | 11 | 18 | |
Female gender | 75.5% | 79.2% | 72.7% | 72.2% | 0.850 |
Age | 78.2 (69.1; 83.7) | 73.6 (69.1; 82.1) | 79.6 (78.1; 84.6) | 76.6 (71.4; 82.6) | 0.834 |
Severe COVID-19 | 13 (22.8%) | 9 (32.1%) | 1 (9.1%) | 3 (16.7%) | 0.120 |
Duration* | 10 (4; 14) | 10 (8; 15) | 10 (7; 19) | 10 (3; 13) | 0.142 |
Fever | 45.3% | 54.2% | 27.3% | 44.4% | 0.331 |
Headache | 22.6% | 33.3% | 9.1% | 16.7% | 0.185 |
Myalgias | 30.2% | 54.2% | 18.2% | 5.6% | 0.002 |
Arthralgias | 26.4% | 50.0% | 9.1% | 5.6% | 0.002 |
Fatigue | 54.7% | 70.8% | 54.5% | 33.3% | 0.054 |
Rhinitis | 32.1% | 25.0% | 27.3% | 44.4% | 0.381 |
Throat pain | 17.0% | 25.0% | 0.0% | 16.7% | 0.188 |
Anosmia | 26.4% | 45.8% | 27.3% | 0.0% | 0.004 |
Dysgeusia | 20.8% | 41.7% | 9.1% | 0.0% | 0.003 |
Chest pain | 15.1% | 25.0% | 9.1% | 5.6% | 0.180 |
Dyspnoea | 20.8% | 33.3% | 18.2% | 5.6% | 0.087 |
Cough | 47.2% | 50.0% | 36.4% | 50.0% | 0.722 |
Respiratory insufficiency | 18.9% | 33.3% | 9.1% | 5.6% | 0.049 |
Abdominal pain | 13.2% | 20.8% | 9.1% | 5.6% | 0.317 |
Nausea, vomiting | 0.0% | 0.0% | 0.0% | 0.0% | N/A |
Diarrhoea | 11.3% | 20.8% | 9.1% | 0.0% | 0.105 |
Thrombotic complications | 5.7% | 4.2% | 0.0% | 11.1% | 0.414 |
Data are median (IQR) or n (%). *Recorded in days. N/A not applicable