Table 5.

Quantitative comparison of sputum positivity: sensitivity and specificity across assays

Response	Predictor	Sensitivity	Specificity
CFU Positivity	LAM Positivity	0.944	0.956
	MGIT Positivity	0.995	0.926
MGIT Positivity	CFU Positivity	0.92	0.947
	LAM Positivity	0.993	0.942
CFU or MGIT Positivity	LAM Positivity	0.934	0.942

CFU positivity is defined as the presence of visible growth on solid media, MGIT positivity is defined as a MGIT-TTD value less than 42 days, and LAM positivity is defined as a value above the LLOQ of 1.176 log₁₀ pg/mL

CFU, colony-forming units; LAM, lipoarabinomannan; LLOQ, lower limit of quantitation; MGIT, Mycobacterium Growth Indicator Tube; TTD, time to detection