Table 3.
Multivariate Cox Regression Analysis of PFS and OS for All NSCLC Patients
| Variables | PFS | P-value | OS | P-value |
|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | |||
| Age (>60/≤60) | 0.821 (0.686–0.983) | 0.032* | - | - |
| Smoking status (current or past/never) | 1.222 (0.999–1.495) | 0.051 | - | - |
| Histology (ADC/non-ADC) | 0.283 (0.174–0.462) | 0.000* | - | - |
| Liver metastasis (yes/no) | 1.233 (0.900–1.691) | 0.193 | 1.411 (0.939–2.121) | 0.098 |
| Bone metastasis (yes/no) | 0.955 (0.783–1.166) | 0.653 | 1.084 (0.817–1.439) | 0.576 |
| Number of metastasis sites (>2/≤2) | 1.409 (1.106–1.795) | 0.005* | 1.277 (0.911–1.791) | 0.156 |
| AAPR (>0.47/≤0.47) | 0.813 (0.673–0.984) | 0.033* | 0.629 (0.476–0.830) | 0.001* |
Note: *P<0.05.
Abbreviations: AAPR, albumin-to-alkaline phosphatase ratio; ADC, adenocarcinoma; CI: confidence interval; HR: hazard ratio; NSCLC, non-small-cell lung cancer; OS, overall survival; PFS, progression-free survival.