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. 2022 Mar 29;16:863–871. doi: 10.2147/DDDT.S354205

Figure 5.

Figure 5

Clotrimazole regulates EMT through the ERK pathway. (A and B) The Vimentin, N-cadherin, and E-cadherin levels in HCC cells treated with clotrimazole (20μM) alone or combinate with honokiol (10μM). (C and D) The ERK, p-ERK, p65 and p-p65 levels in HCC cells treated with clotrimazole alone or combinate with honokiol (10μM). The results of quantification are expressed as the mean ± SD (n=3), *P<0.05, **P< 0.01, ***P<0.001 vs the control group (without clotrimazole and honokiol group), #P<0.05 vs clotrimazole treated group.