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Current Children’s Oncology Group Rhabdomyosarcoma Risk Stratification
| Risk Group | Stage | Clinical Group | Age | Fusion Status |
|---|---|---|---|---|
| Low | 1 | I, II, III (orbit only) | Any | FOXO1 − |
| 2 | I, II | |||
| Intermediate | 1 | III (non-orbit) | Any | FOXO1 − |
| 1, 2, 3 | I, II, III | FOXO1 + | ||
| 2, 3 | III | FOXO1 − | ||
| 3 | I, II | FOXO1 − | ||
| 4 | IV | <10 years | FOXO1 − | |
| High | 4 | IV | >10 years | FOXO1 − |
| Any | FOXO1 + |
