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. 2022 Apr 2;10(6):1622–1634.e4. doi: 10.1016/j.jaip.2022.03.017

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SARS-CoV-2 anti-spike antibody levels (U/mL) (A), SARS-CoV-2 pseudovirus neutralization values (pNT50) (B), and SARS-CoV-2 anti-RBD antibody titers (U/mL) (C), shown in log scale and compared between predominant antibody deficiency (PAD) diagnoses as indicated. Symbols represent unique individuals, bars represent geometric means (±95% confidence intervals) of total indicated patients (n), and shading represents the assay lower limit of detection (LLD) or reactivity, respectively. ∗P < .05; ∗∗P < .01. APDS, Activated PI3K Delta Syndrome; CVID, common variable immunodeficiency; def, deficiency; PHG, primary hypogammaglobulinemia; SAD, specific antibody deficiency.