Table 3. Case examples of publications representing big splashes and broad ripple effects in the Georgia CTSA pediatrics program publication portfolio.

Big splashes
(a)	‘Effect of a low free sugar diet vs. usual diet on nonalcoholic fatty liver disease in adolescent boys: A randomized clinical trial’. Schwimmer, et al., JAMA. 2019 (40); AAS =538
	o Authors supported via Georgia CTSA nursing/lab resources and Informatics and Biostatistical consultations • Published in the Journal of the American Medical Association (JAMA), JIF =51.3 • Mentioned in 28 news articles, e.g., 2019 New York Times article: ‘To Fight Fatty Liver, Avoid Sugary Foods and Drinks’ • Mentioned in more than 600 Tweets to over 2 million Twitter followers, e.g., @DrKristieLeong: “Non-alcoholic fatty liver disease is a growing problem even in children. A recent study found that a reduced #sugar diet over 8 weeks led to significant improvement in markers of liver #health #liverdisease” • Recommended by a faculty member in Faculty Opinions
(b)	‘Tisagenlecleucel in children and young adults with B-cell lymphoblastic leukemia’. Maude, et al. NEJM. 2018 (41); AAS =413
	o Georgia CTSA author (M. Qayed) supported via a pilot grant and a KL2 training grant • Published in the New England Journal of Medicine (NEJM), JIF =70.7 • Mentioned in more than 150 tweets to over 1 million followers, e.g.: @dr_mark_russell: “Will be interested to see the impact of CAR-T cell therapy on #PedsICU haem/onc children—anyone seen many children who have received it?” • Mentioned in 8 science blogs, e.g.: 2018 Hematology Times article ‘CAR T-cell therapy produces durable CRs in ALL’ • Mentioned in 37 news outlets around the world, e.g., BBC News, Deutsches Arzteblatt, MedIndia • Downloaded by Mendeley reference manager program readers 719 times
(c)	‘Acetaminophen versus ibuprofen in young children with mild persistent asthma’. Sheehan, et al. NEJM. 2016 (42); AAS =332
	o Georgia CTSA author (A. Fitzpatrick) supported via Georgia CTSA clinical research space and laboratory resources and a KL2 training grant • Published in the New England Journal of Medicine (NEJM), JIF =70.7 • Mentioned in 41 news stories from 27 outlets, e.g., Physician’s Briefing, Deutsches Arzteblatt, MedicalXpress • Mentioned in 3 academic blog posts, e.g., Vector, BMJ Blogs • Mentioned in more than 190 tweets to over 1 million followers. e.g., @AllergyKidsDoc: “Re-reading great @NEJM article from last yr: No difference in #asthma attacks for kids receiving tylenol vs. ibuprofen”
Broad ripple effects
(d)	‘Consumption of added sugars is decreasing in the United States’. Welsh, et al. Am J Clin Nutr. 2011 (43); AAS =412
	o Authors supported via Georgia CTSA pilot grant • Cited in over 300 academic articles; 10 times the expected citation rate • Cited in multiple CDC health policy reports, e.g., ‘Consumption of Added Sugar Among U.S. Children and Adolescents, 2005-2008’ • Referenced in Wikipedia article on ‘Sweetened beverage’
(e)	‘A randomized controlled crossover trial with delayed-release cysteamine bitartrate in nephropathic cystinosis: effectiveness on white blood cell cystine levels and comparison of safety’. Langmon, et al. Clin J Am Soc Nephrol. 2012 (44); AAS =13
	o Georgia CTSA author (L. Greenbaum) supported via clinical research space and laboratory resources • Cited in multiple patents on cysteamine formulation and manufacture: ‘Methods for Storing Cysteamine Formulations and Related Methods of Treatment’, ‘Delayed Release Cysteamine Bead Formation, and Methods of Making and Using Same’
(f)	‘Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network’. Stoll, et al. Pediatrics. 2010 (45); AAS =86
	o Georgia CTSA author (B. Stoll) supported via clinical research services • Cited in over 1,000 academic articles, including citations in 88 clinical articles; 51 times the expected citation rate • Cited in multiple international and CDC health policy reports, e.g., ‘Health, United States, 2015: in brief’ • Cited in a patent application: ‘Biomarker Pairs of Preterm Birth’

AAS, Altmetric Attention Score, JIF, journal impact factor.