Table 2. Treatment of children with OMS-NB (N=14).
Patient No. | Gender | Age at OMS onset (months) | Stage (INRG) | Immune therapy | Tumor resection | Course of chemotherapy | |
---|---|---|---|---|---|---|---|
Pre-operative | Post-operativea | ||||||
1 | Male | 20 | L1 | I, M | CR | 0 | 3 |
2 | Male | 27 | L1 | M, P | CR | 0 | 0 |
3 | Female | 16 | L1 | I, A, M, R | CR | 0 | 4 |
4 | Male | 54 | L2 | P | CR | 0 | 10 |
5 | Female | 13 | L2 | – | CR | 1 | 6 |
6 | Female | 24 | L1 | – | MRD | 0 | 0 |
7 | Male | 19 | L2 | – | CR | 0 | 6 |
8 | Male | 16 | L2 | I | CR | 4 | 6 |
9 | Male | 21 | L1 | I, P | CR | 0 | 6 |
10 | Female | 24 | L1 | I, M, P | CR | 2 | 0 |
11 | Male | 39 | L2 | – | CR | 4 | 8 |
12 | Male | 14 | L2 | I | CR | 2 | 4 |
13 | Female | 18 | L2 | I, P | MRD | 2 | 3 |
14 | Male | 22 | L1 | I, P | CR | 1 | 2 |
a, the courses of post-operative chemotherapy were counted before relapse if the patient suffered relapse. OMS, opsoclonus myoclonus syndrome; NB, neuroblastoma; INRG, International Neuroblastoma Risk Group; CR, complete resection; MRD, microscopic residual disease; M, methylprednisolone; I, intravenous immunoglobulin; P, prednisone; A, adrenocorticotropic hormone; R, rituximab.