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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Clin Cancer Res. 2022 Apr 1;28(7):1250–1257. doi: 10.1158/1078-0432.CCR-21-1240

Table 1.

Published studies on factors related to prediction of immune-related adverse events (irAEs).

Factors Associated with irAEs Cited References
Pre-existing autoimmune disease van der Kooij et al. (15), Fountzilas et al. (16), Alexander et al. (17), Abu-Sbeih et al. (18), Abdel-Wahab et al. (19), Michailidou et al. (20), Yeung et al. (21), Abdel-Wahab et al. (22), Cappelli et al. (24), Stamatouli et al. (25), Toi et al. (26), de Moel et al. (27)
Sex and body mass index Valpione et al. (29), Guzman-Prado et al. (30), Shah et al. (31), Young et al. (32)
Response to ICI Giacomo et al. (33), Das et al. (34), Xing et al. (35), Jing et al. (36), Haratani et al. (39), Wang et al. (40), Bomze et al. (41)
Circulating cytokines and immune cells Valpione et al. (29), Tarhini et al. (42), Lim et al. (43), Tyan et al. (44), Eun et al. (45), Pavan et al. (46), Chu et al. (47)
Inherited genetic variants Queirolo et al. (48), Bins et al. (49)
Microbiome Andrews et al. (51), Dubin et al. (52)