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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Clin Cancer Res. 2022 Apr 1;28(7):1313–1322. doi: 10.1158/1078-0432.CCR-21-3729

Figure 2. Decrease in DNA methylation from Day 1 to Day 5 in Cycle 1 in treatment non-responders and responders.

Figure 2

Methylation, measured as described, was compared between Day 5 and Day 1 samples, and changes in methylation were compared between in treatment non-responders and responders. There was a trend toward greater decrease in treatment responders, compared to non-responders, albeit with small patient numbers (p=0.07, two-tailed t-test). CRi = Complete remission with incomplete count recovery; HI = Hematologic improvement; NR = No response.