Skip to main content
. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: J Physiol. 2022 Feb 1;600(7):1651–1666. doi: 10.1113/JP281873

Figure 1. TRPV1 antagonists dilate isolated skeletal muscle arterioles.

Figure 1.

A and B, BCTC (1 μM) dilates isolated, pressurized (60 mmHg) skeletal muscle arteries from wild-type mice (n = 3 mice, 5 arteries) but not TRPV1-null mice (n = 3 mice, 4 arteries, nested T-test). The response to 40 mM KCl is shown for reference. C and D, AMG517 (3 μM) selectively dilates arteries from WT but not TRPV1-null mice (n = 3 mice, 3 arteries, unpaired t-test). E and F, BCTC fails to dilate mesenteric arteries from WT mice (n = 4 arteries, 4 mice, unpaired t-test, P = 0.764).