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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: J Physiol. 2022 Feb 1;600(7):1651–1666. doi: 10.1113/JP281873

Figure 4. BCTC transiently decreases systemic blood pressure.

Figure 4.

A-C, Blood pressure (BP) changes in rats during bolus IV BCTC or AMG517 (n = 5, one-way ANOVA Tukey’s Multi. comp.). D and E, BP changes in WT and TRPV1-null mice in response to IV infusion (20 s) of BCTC (n = 6) and sodium nitroprusside (n = 4, unpaired t-test). Mean arterial pressure is shown in red. F, BP changes in response to IV BCTC in conscious, sensory nerve-ablated mice (n = 5, unpaired t-test). G Heart-rate changes in WT and TRPV1-null mice (n = 6, unpaired t-test) in response to IV BCTC. H and I, Representative changes in BP and heart-rate in response to prolonged (4 minute) infusion of BCTC.