Fig. 4.

Esomeprazole suppresses autophagy in HUVEC treated with hypoxia and L-NAME. (a, a′, a″) Cell migrations upon hypoxia and L-NAME treatment were measured using transwell-migration assays. (b) Quantification of cell migration of (a, a′, a″). (c) LC3B proteins levels were detected via Western blot. (c′) Plot depicting the quantification of LC3B expression levels. (d–i″) The LC3B and P53 expressions were visualized using immunofluorescence staining. All data are representative of three independent experiments: *P < 0.05, **P < 0.01