Table 1.
Clinical scores determining IA risk of rupture or growth (adapted from Greving et al. [28], Etminan et al. [18], and Backes et al. [1])
| PHASES score [28] | UIAT score [18] | ELAPSS score [1] | |
|---|---|---|---|
| Aneurysm | - Size of the aneurysm (< 7.0 mm, 7.0–9.9 mm, 10.0–19.9 mm, ≥ 20.0 mm) | - Maximum diameter (≤ 3.9 mm, 4.0–6.9 mm, 7.0–12.9 mm, 13.0–24.9 mm, ≥ 25.0 mm) | - Size of the aneurysm (1.0–2.9 mm, 3.0–4.9 mm, 5.0–6.9 mm, 7.0–9.9 mm, ≥ 10.0 mm) |
| - Site of IA (ICA, MCA, ACA/Pcom/posterior) | - Location (BasA bifurcation, vertebral/basilar artery, AcomA or PcomA) | - Location of the IA (ICA/ACA/Acom, MCA, Pcom/posterior) | |
|
- Morphology (irregularity or lobulation, size ratio > 3 or aspect ratio > 1.6) - IA growth on serial imaging - IA de novo formation on serial imaging - Contralateral steno-occlusive vessel disease |
- Shape of the IA (regular or irregular) | ||
| Patient | - Age (< or ≥ 70 years) | - Age (< 40 years, 40–60 years, 61–70 years, 71–80 years, > 80 years) | - Age (≤ or > 60 years) |
|
- Early SAH from another IA (yes/no) - Population (North American, European (other than Finnish), Japanese, Finnish) - Hypertension (yes/no) |
- Risk factor incidence (previous SAH from a different IA, familial IA or SAH, Japanese/Finnish/Inuit ethnicity, current cigarette smoking, hypertension, APKD, current drug and/or alcohol abuse) |
- Earlier SAH (yes/no) - Population (North American, China, Europe (other than Finland), Japan, Finland) |
|
|
- Clinical symptoms related to unruptured IA (cranial nerve deficit, clinical or radiological mass effect, thromboembolic events from the IA, epilepsy) - Reduced quality of life due to fear of rupture - Aneurysm multiplicity - Life expectancy due to chronic and/or malignant diseases (< 5 years, 5–10 years, < 10 years) - Comorbid diseases (neurocognitive disorder, coagulopathies, thrombophilic diseases, psychiatric disorder) |
|||
| Treatment |
- Age-related risk (< 40 years, 40–60 years, 61–70 years, 71–80 years, > 80 years) - Aneurysm size-related risk (< 6.0 mm, 6.0–10.0 mm, 10.1–20.0 mm, > 20.0 mm) - Aneurysm complexity-related risk (high/low) - Intervention-related risk (constant) |
ACA anterior cerebral artery, AcomA anterior communicating artery, APKD autosomal-polycystic kidney disease, BasA basilar artery, IA intracranial aneurysm, ICA internal carotid artery, MCA middle cerebral artery, Pcom posterior communicating artery, SAH subarachnoid hemorrhage