Table 2.

Comparison of Characteristics Between Isotretinoin and Controls

	Control	Isotretinoin	P Value
Meibomian gland Acini size (upper lid), mm2	0.443 ± 0.048	0.438 ± 0.051	0.809
Ductal epithelial thickness, µm	8.39 ± 1.83	15.91 ± 3.79	0.0001*
Conjunctival goblet cell, cell/mm	12.30 ± 2.10	8.28 ± 1.06	0.0412*
Oil red O mean optical density	77.81 ± 19.15	43.76 ± 15.26	0.0031*

^*Statistically significant at P ≤ 0.05.