Table 1.
Summary statistics for those who did not enter the CRIC study with pre-existing PAD, stratified by development of PAD during the study period.
| No PAD (n = 2674) | Incident PAD (n = 639) | p-value | ||
|---|---|---|---|---|
| Age | < 45 years | 328 (12.3%) | 53 (8.3%) | 0.002 |
| 45 to less than 65 years | 1507 (56.4%) | 350 (54.8%) | ||
| ≥ 65 years | 839 (31.4%) | 236 (36.9%) | ||
| Annual Household Income | Below $25,000 | 768 (28.7%) | 255 (39.9%) | <0.001 |
| $25,000–$50,000 | 768 (28.7%) | 190 (29.7%) | ||
| $50,000-$100,000 | 675 (25.2%) | 149 (23.3%) | ||
| Above $100,000 | 463 (17.3%) | 45 (7.0%) | ||
| Education Level | Some High School | 389 (14.5%) | 127 (19.9%) | <0.001 |
| High School Grad | 439 (16.4%) | 125 (19.6%) | ||
| Some College | 784 (29.3%) | 213 (33.3%) | ||
| College Grad | 1062 (39.7%) | 174 (27.2%) | ||
| Male Gender | 1588 (59.4%) | 281 (44.0%) | <0.001 | |
| Black Race | 1058 (39.6%) | 333 (52.1%) | <0.001 | |
| eGFR (mL/min per 1.73 m2) | Below 30 | 296 (11.1%) | 108 (16.9%) | <0.001 |
| 30–60 | 1618 (60.5%) | 436 (68.2%) | ||
| Above 60 | 760 (28.4%) | 95 (14.9%) | ||
| History of CVD | 623 (23.3%) | 204 (31.9%) | <0.001 | |
| History of DM | 1120 (41.9%) | 336 (52.6%) | <0.001 | |
| History of Hypertension | 2198 (82.2%) | 587 (91.9%) | <0.001 | |
| History of High Cholesterol | 1997 (74.7%) | 527 (82.5%) | <0.001 | |
| Tobacco Use | 251 (9.4%) | 129 (20.2%) | <0.001 | |
| Alcohol Use | 686 (25.7%) | 115 (18.0%) | <0.001 | |
| Medication Use | Statin Use | 1389 (52.3%) | 379 (59.9%) | <0.001 |
| Antiplatelet Use | 1144 (43.1%) | 303 (47.4%) | 0.028 | |
| Anticoagulant Use | 166 (6.2%) | 36 (5.6%) | 0.59 | |
| Body Mass Index | Below 25 | 407 (15.3%) | 87 (13.6%) | <0.001 |
| 25–30 | 835 (31.3%) | 161 (25.2%) | ||
| Above 30 | 1424 (53.4%) | 391 (61.2%) | ||
| Urine Sodium Concentration, mmol/L (SD) | 83.0 (35.5) | 82.2 (34.1) | 0.62 | |
| Urine Protein/Creatinine Ratio (SD) | 0.68 (1.9) | 0.86 (2.0) | 0.035 | |
| Cause of Renal Disease | Diabetes | 518 (19.4%) | 167 (26.1%) | <0.001 |
| Hypertension | 418 (15.6%) | 94 (14.7%) | ||
| Other | 432 (16.2%) | 73 (11.4%) | ||
| Unknown | 1306 (48.8%) | 305 (47.4%) | ||
| CRIC Site | University of Pennsylvania | 334 (12.5%) | 93 (14.6%) | <0.001 |
| The Johns Hopkins University | 357 (13.4%) | 98 (15.3%) | ||
| Case Western Reserve University | 331 (12.4%) | 149 (23.3%) | ||
| University of Michigan | 409 (15.3%) | 46 (7.2%) | ||
| University of Illinois at Chicago | 442 (16.5%) | 128 (20.0%) | ||
| Tulane University Health Science Center | 305 (11.4%) | 51(8.0%) | ||
| Kaiser Permanente of Norther California | 496 (18.5%) | 74 (11.6%) |
PAD: Peripheral Artery Disease, CVD: Cardiovascular Disease, DM: Diabetes Mellitus