Table 2.

Effect of dietary ion intake on serum K⁺ in WT and pendrin-null mice

	Ions Added to the Diet					Serum K+ Concentration, meq
	Na+	K+	Cl−	OtherTreatments	Strain	Male	Female
Treatment 1	−	−	−		WT	3.9 ± 0.1 (n = 11)	3.8 ± 0.2 (n = 3)
					KO	3.1 ± 0.1 (n = 11)*	3.0 ± 0.3 (n = 4)
Treatment 2	+	−	+		WT	4.0 ± 0.3 (n = 4)	4.4 ± 0.1 (n = 6)
					KO	4.2 ± 0.3 (n = 3)	4.1 ± 0.2 (n = 5)
Treatment 3	−	−	−	Amiloride	WT	5.5 ± 0.3 (n = 9)	4.3 ± 0.1 (n = 7)
					KO	5.7 ± 0.3 (n = 10)	4.5 ± 0.1 (n = 6)

Data are means ± SE; n, number of mice studied. Mice were on a C57 Bl/6 background. *P < 0.05. KO, knockout; WT, wild type.