TABLE 1.
Patient demographics according to the interstitial lung abnormality scoring
| Characteristics | ILA score | |||
|---|---|---|---|---|
| 0 or 1 (n = 209) | 2 (n = 45) | Total (n = 254) | p‐value | |
| Age (years) | 73 (71,76) | 73 (71.5, 75.5) | 73 (71,76) | 0.45 |
| Male | 89 (42.6) | 41 (91.1) | 130 (51.2) | <0.001 |
| Smoking status | <0.001 | |||
| Never | 137 (65.6) | 3 (6.7) | 140 (55.1) | |
| Former/current | 72 (34.4) | 42 (94.4) | 114 (44.9) | |
| Pack years of smoking | 0 (0, 21.3) | 40 (27, 50) | 0 (0, 30) | <0.001 |
| BMI, kg/m2 | 23.5 (21.6, 25.7) | 24.0 (21.5, 25.6) | 23.6 (21.6, 25.6) | 0.15 |
| DM | 61 (29.2) | 18 (40) | 79 (31.1) | 0.11 |
| HTN | 120 (57.4) | 21 (46.7) | 141 (55.5) | 0.13 |
| Cardiovascular disease | 20 (9.6) | 4 (8.9) | 24 (9.4) | 0.58 |
| Double primary cancer | 15 (7.2) | 2 (3.0) | 17 (6.7) | 0.39 |
| Previous cancer history | 38 (18.2) | 8 (17.8) | 46 (18.1%) | 0.57 |
| PFT | ||||
| FVC (% pred) | 90 (83, 99) | 86 (82, 95.5) | 89 (83,99) | 0.17 |
| FEV1 (% pred) | 99 (91, 108) | 94 (88.8, 109.5) | 99 (90, 108) | 0.28 |
| FEV1/FVC | 76.0 (73.0, 79.7) | 73.0 (70.7, 77.5) | 75.6 (72.5, 79.3) | 0.01 |
| DLCO (% pred) | 105 (90.8, 118.6) | 80 (67.0, 93.5) | 101.5 (86.0, 117.6) | <0.001 |
| Emphysema (≥5%) | 10 (4.8) | 13 (28.9) | 23 (9.1) | <0.001 |
Note: Continuous variables are presented as median values (interquartile range). Values for the number of patients are presented as numbers and percentages (in parenthesis). Bold values indicate that p < 0.05.
Abbreviations: BMI, body mass index; DLCO, diffusing capacity of the lung for CO; DM: diabetes mellitus; FEV1, forced expiratory volume in one second; FVC, forced vital capacity; HTN, hypertension; ILA, interstitial lung abnormality.