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. 2022 Mar 29;4(4):149–157. doi: 10.1253/circrep.CR-21-0165

Table 3.

Study Used to Answer Clinical Question 3

Underlying
disease
Study
design
Study n Country Intervention Duration
(months)
Comparison Population Outcome
Hypertension Comparative Yamagishi
et al22
193 Japan Counseling guidance
program
9 Full-intervention vs. minimal-
intervention communities
Hypertension patients in
Akita Prefecture, Japan
The prevalence and incidence of stroke were consistently lower in the full- than minimal-
intervention community throughout the same time period
The incremental cost was −JPY28,358 per capita over 24 years
Budget impact: cost of public health services per capita, 4,741 JPY/year; cost of hypertension
treatment per capita, −7,126 JPY/year; cost of stroke treatment per capita, −2,500 JPY/year;
total cost per capita, −4,884 JPY/year