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. 2022 Mar 30;15:2121–2139. doi: 10.2147/JIR.S348850

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© 2022 Yuan et al.

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Serum apelin-13 levels increased in patients with sepsis and sepsis-associated ARDS. (A) Serum apelin-13 levels in healthy controls (n=13) and 34 patients with sepsis (n=34, including nine patients with sepsis-associated ARDS). Apelin-13 levels in serum were measured by ELISA. (B) Temporal changes of apelin-13 serum levels in three patients with sepsis-associated ARDS (patient 5, 6, and 7). Apelin-13 levels were measured by ELISA at the indicated time points after the visit for sepsis diagnosis. ****P<0.0001 versus healthy group.

Abbreviations: ARDS, acute respiratory distress syndrome; ELISA, enzyme linked immunosorbent assay.