Pictorial representation of the exogenous and endogenous parameters reversibly influencing biochemical and mechanical properties of smart materials. Figure permissions - (top left): Reproduced with permission from reference [17], Copyright (2016) American Chemical Society, (bottom left): Reproduced with permission from reference [65] Copyright 2020 John Wiley and Sons, (top right): Reproduced with permission from reference [66], Copyright (2016) Creative Commons Attribution License 4.0 International, (bottom right): Reproduced from reference[67], Copyright (2011) with permission from American Chemical Society.