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. 2022 Mar 27;2022:4086935. doi: 10.1155/2022/4086935

Figure 5.

Figure 5

miR-181b directly interacted with Notch1 in VSMCs. (a) TargetScan database predicts the binding sequence between Notch1 and miR-181b. (b) Pearson's correlation coefficient determined the correlations between Notch1 and circ_TNPO1 or miR-181b in AS patients' serum. (c) Dual-luciferase reporter assay determined the direct interaction of Notch1 with miR-181b in VSMCs.P < 0.05. (d) Effects of miR-181b mimic and miR-181b inhibitor on Notch1 protein expression levels in VSMCs.