Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
miR-155 and the miR-183/96/182 cluster modulate P. aeruginosa keratitis by regulating the function of macrophages (Mϕ). A. miR-155 targets the expression of Rheb, which enhances the production of iNOS and mTOR activity to promote phagocytosis and intracellular bacterial killing. B. miR-183/96/182 targets Nox2, important in ROS and RNS production, to promote phagocytosis/intracellular bacterial killing, and DAP12, which limits production of pro-inflammatory cytokines.
