TABLE 6.
Local and Systemic Adverse Events (AEs) Reported after the third booster dose of BNT162b2 Vaccine Stratified by Antibody Response.
| AEs | Total cohort | Negative | Positive | p value |
|---|---|---|---|---|
| (N = 97) | (N = 13) | (N = 84) | ||
| Local AEs, n (%) | ||||
| Pain at injection site | 50 (51.5) | 5 (38.5) | 45 (53.6) | 0.31 |
| Swelling | 9 (9.3) | 2 (15.4) | 7 (8.3) | 0.41 |
| Redness | 10 (10.3) | 1 (7.7) | 9 (10.7) | 0.74 |
| Systemic AEs, n (%) | ||||
| Fever | 4 (4.1) | 0 (0) | 4 (4.8) | 0.42 |
| Fatigue | 31 (31.96) | 2 (15.4) | 29 (34.5) | 0.17 |
| Headache | 17 (17.5) | 0 (0) | 17 (20.2) | 0.07 |
| Myalgia | 17 (17.5) | 0 (0) | 17 (20.2) | 0.07 |
| Chills | 3 (3.1) | 1 (7.7) | 2 (2.4) | 0.3 |
| Nausea/vomiting | 3 (3.1) | 0 (0) | 3 (3.6) | 0.49 |
| Paresthesia | 2 (2.1) | 0 (0) | 2 (2.4) | 0.57 |
| Any local AE, n (%) | 53 (54.6) | 6 (46.2) | 47 (56) | 0.51 |
| Any sytemic AE, n (%) | 40 (41.2) | 2 (15.4) | 38 (45.2) | 0.04* |
| Any AE, n (%) | 68 (70.1) | 7 (53.6) | 61 (72.6) | 0.17 |
a
<0.05.
When p value is significant, below 0.05 or below 0.01 the values are bolded.