Table 4.
Age and gender adjusted univariate logistic regression analysis for side effects and disease flares (patients with rheumatic diseases were considered as the reference category)
| CoronoVac | BioNTech | |||
|---|---|---|---|---|
| Odds ratio (95% CI) | p | Odds ratio (95% CI) | p | |
| Any side effect | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
1.014 (0.630–1.634) 1.057 (0.634–1.764) |
0.953 0.831 |
1.357 (0.741–2.488 0.831 (0.471–1.466) |
0.323 0.522 |
| Arm pain | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
0.948 (0.561–1.60) 0.960 (0.558–1.653) |
0.841 0.884 |
1.012 (0.626–1.635) 0.986 (0.608–1.600) |
0.962 0.956 |
| Fatigue/weakness | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
0.897 (0.454–1.769) 0.684 (0.331–1.414) |
0.753 0.306 |
1.832 (1.161–2.891) 1.459 (0.928–2.293) |
0.009 1.459 |
| Headache | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
1.487 (0.684–3.232) 1.309 (0.582–2.946) |
0.317 0.515 |
4.394 (2.553–7.562) 1.215 (0.681–2.168) |
< 0.001 0.509 |
| Back pain or myalgia | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
0.818 (0.216–3.106) 0.835 (0.218–3.208) |
0.768 0.793 |
1.749 (0.923–3.313) 1.600 (0.855–2.995) |
0.087 0.141 |
| Joint pain | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
0.556 (0.145–2.135) 0.552 (0.143–2.136) |
0.393 0.390 |
1.784 (0.846–3.760) 2.954 (1.506–5.793) |
0.128 0.002 |
| Fever | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
2.702 (0.956–7.637) 1.939 (0.610–6.166) |
0.061 0.262 |
1.922 (1.071–3.449) 1.923 (1.093–3.383) |
0.029 0.023 |
| Nausea/vomiting | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
1.653 (0.556–4.912) 0.878 (0.225–3.431) |
0.366 0.852 |
1.375 (0.632–2.993) 0.974 (0.443–2.140) |
0.422 0.947 |
| Diarrhea | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
2.314 (0.320–14.233) 2.032 (0.297–13.885) |
0.434 0.470 |
2.055 (0.736–5.739) 1.698 (0.611–4.721) |
0.169 0.310 |
| Loss of appetite | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
NA | NA |
0.557 (0.180–1.728) 1.296 (0.584–2.878) |
0.311 0.524 |
| Cough | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
NA | NA |
2.400 (0.493–11.695) 1.744 (0.324–9.383) |
0.279 0.517 |
| Allergic reaction | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
NA | NA | NA | NA |
| Local reaction | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
NA | NA |
0.958 (0.393–2.331) 0.997 (0.436–2.282) |
0.924 0.955 |
| Lymph node swelling | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
NA | NA |
1.611 (0.282–9.792) 2.859 (0.695–11.764) |
0.575 0.146 |
| Vertigo | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
NA | NA |
0.696 (0.067–7.256) 0.452 (0.043–4.741) |
0.762 0.508 |
| Any cardiovascular complaints | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
1.642 (0.358–7.527) 0.722 (0.079–6.641) |
0.523 0.774 |
0.300 (0.035–2.570) 0.976 (0.263–3.626) |
0.272 0.971 |
| Miscellaneous complaints, n (%) | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
0.814 (0.088–7.518) 1.489 (0.254–8.748) |
0.856 0.659 |
2.550 (0.855–7.608) 0.489 (0.100–2.402) |
0.093 0.379 |
| AEs requiring medical attendance | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
2.110 (0.694–6.418) 1.160 (0.291–4.622) |
0.188 0.834 |
1.369 (0.514–3.650) 0.490 (0.131–1.832) |
0.530 0.289 |
| Thromboembolic/cardiovascular events | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
6.758 (0.539–84.654) 7.810 (0.602–101.252) |
0.138 0.116 |
2.198 (0.451–10.705) 1.836 (0.341–9.897) |
0.330 0.480 |
| Disease flares | ||||
|
Behçet’s syndrome Familial Mediterranean fever |
3.428 (0.790–14.872) 7.830 (2.252–27.223) |
0.100 0.001 |
9.286 (2.399–35.946) 4.673 (1.258–17.362) |
0.001 0.021 |
NA: not applicable due to zero or low number of values