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. 2022 Mar 21;13:818522. doi: 10.3389/fneur.2022.818522

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Copyright © 2022 Ling, Chen, He, Feng, Weng, Cheng, Rong and Xie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Head-to-head comparisons for efficacy and safety (primary outcomes) of 11 drugs. Drugs are reported in efficacy order sorted from top left to bottom right. Data are SMD (95% CrI) and OR (95% CrI) in the column-defining treatment compared with the row-defining treatment. For efficacy (pain relief for around 4 weeks), SMD lower than 0 favors the column-defining treatment. For safety (adverse events), OR lower than 1 favors near the top left one. To obtain OR for comparisons in the opposite direction, reciprocals should be taken. Significant results are in bold. SMD, standard mean deviation; OR, odds ratio; CrI, credible interval; BTXA, botulinum toxin-A.