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Network and representative clusters of DN. Key pathogenesis of DN includes the complement and coagulation cascades, adipocytokine signaling pathway, TNF signaling pathway, HIF-1 signaling pathway, and AMPK signaling pathway. (A) A total of 9,621 pairs of genes were identified from GeneCards and OMIM. (B–F) Major Cluster of Genes Related to Diabetic Nephropathy and (G) KEGG enrichment analysis on the DN pathogenesis
