Fig. (3).

Mechanisms of action proposed for Lavandula angustifolia Mill EOs Lavandula hybrida Rev. and Rosa Damascena Mill. and in in vivo models for neurological disorders. The study was conducted through an in vivo model of dementia induced by scopolamine. Treatment with EOs of Lavandula angustifolia Mill. and Lavandula hybrida significantly increased the antioxidant activities of enzymes SOD, GPX and CAT and reduced total GSH content while decreasing MDA levels. In addition, these EOs showed activity on DNA fragmentation, thus the cleavage patterns were absent in the treated groups suggesting an antiapoptotic effect. The EO of Rosa damascene Mill. demonstrates a similar effect because it acts to prevent important oxidative damage caused by intraperitoneal injection with high doses of L-dopa, thus demonstrating the antioxidant effect that is possibly mentioned as preventing damage to DNA. (A higher resolution/colour version of this figure is available in the electronic copy of the article).