Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 1;10(4):e004114. doi: 10.1136/jitc-2021-004114

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

Correlation between PD-1 and A2aR expression and dysfunctional CD8⁺ T cells identified by single-cell RNA sequencing. (A) Total and separate UMAP plots of CD8⁺ T cell clusters from four diffuse large B-cell lymphoma (DLBCL) samples in the GSE182434 cohort. (B) The identification of dysfunctional CD8⁺ T cells according to the expression of five marker genes. (C) The percentage of dysfunctional CD8⁺ T cells in each patient. (D) The expression of PD-1 and A2aR on CD8⁺ T cells in each patient. (E) The correlation between PD-1 and A2aR expression on CD8⁺ T cells and dysfunctional CD8⁺ T cells by Spearman analysis. A2aR, A2a adenosine receptor; PD-1, programmed cell death protein 1.