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. 2022 Apr 1;10(4):e004114. doi: 10.1136/jitc-2021-004114

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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Survival analysis of patients with DLBCL. PFS and OS of patients with DLBCL based on dysfunctional CD8⁺ T cells (PD-1⁺CD8⁺ T cells) (A, B) and dysfunctional CD8⁺ T cells (A2aR⁺CD8⁺ T cells) (C, D); the ratio of the numbers of CD8⁺ T cells with PD-1 and A2aR expression to the number of overall CD8⁺ T cells (E–H); and different grades of dysfunctional CD8⁺ T cells (I, J). A two-tailed p<0.05 was considered statistically significant. DLBCL, diffuse large B-cell lymphoma; OS, overall survival; PD-1, programmed cell death protein 1; PFS, progression-free survival.