Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 31;10(2):e002699. doi: 10.1136/bmjdrc-2021-002699

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

Exercise and trimetazidine (TMZ) effects on nuclear factor erythroid 2 related factor 2 (Nrf2) signaling pathway and oxidative stress in high-fat diet (HFD) mouse models. (A) Nrf2-mRNA expression was determined by quantitative PCR. (B, C) Nrf2 protein expression was determined by western blot. (D, E) Heme oxygenase-1 (HO-1), NAD(P)H:quinone oxidoreductase 1 (NQO-1) protein expression was determined by western blot. (F, G) Represented the manganese-dependent superoxide dismutase (MnSOD) activity and malondialdehyde (MDA) content, respectively. *,**Represented p<0.05, p<0.01 in comparison with normal diet (ND) group, respectively; ^#,^##represents p<0.05, p<0.01 in comparison with HFD group, respectively. GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HFD+Ex, HFD+exercise group; HFD+TMZ, HFD+TMZ group.