Table: 2.

Description of included studies in the review.

S.N	Authors with citation	Publication year	country	Mean age	Sample size	Design	Intervention modality (prevention or treatment)	Main findings	ROB
1	Moghadam A et al. [18]	2013	Iran	26.5	102	RCT	Effect of acupressure on postoperative nausea and vomiting in cesarean section	Acupressure was shown to be effective for reducing nausea and vomiting.	Low
2	H.Noroozinia et al. [19]	2013	Iran		152	RCT	The Effect of Acupressure on Nausea and Vomiting after Cesarean Section Under Spinal Anesthesia	Acupressure when done 30 min before surgery effectively reduces postoperative nausea and vomiting,	Low
3	M.El-Deeb et al. [20]	2011	Egypt	30	450	RCT	Effect of acupuncture on nausea and/or vomiting during and after cesarean section in comparison with ondansetron	Acupuncture has comparable effectiveness with a single dose of 4 mg ondansetron in PONV prevention and is cost-effective.	Low
4	Pakniat H et al. [21]	2020	Iran	29	180	RCT	The effect of ginger and metoclopramide in the prevention of nausea and vomiting during and after surgery in the cesarean section under spinal anesthesia.	Ginger has the same effectiveness as metoclopramide in reducing nausea and vomiting in patients undergoing cesarean section.	Low
5	Zeraati H et al. [22]	2016	Iran	30	92	RCT	The effect of ginger extract on the incidence and severity of nausea and vomiting after cesarean section under spinal anesthesia.	Ginger extract can be used to reduce nausea and vomiting during cesarean section under spinal anesthesia.	Low
6	Kalava A et al. [23]	2013	USA		239	RCT,	Efficacy of ginger on intraoperative and postoperative nausea and vomiting in elective cesarean section patients.	Ginger has no effect on the overall occurrence of intraoperative nausea and vomiting during cesarean section done under CSE anesthesia	High
7	Rasooli S et al. [24]	2019	Iran	29	110	RCT	Preventing nausea and vomiting using ondansetron and metoclopramide-phenylephrine in cesarean section using spinal anesthesia.	The combination of prophylactic therapy with metoclopramide and ondansetron can significantly reduce intra and PON in patients undergoing CS under spinal anesthesia.	Low
8	Voigt M et al. [25]	2013	Germany	>18	308	RCT,	Prophylaxis of intra-and postoperative nausea and vomiting in patients during cesarean section in spinal anesthesia.	tropisetron 2 mg and metoclopramide 20 mg Prophylaxis for patients undergoing cesarean section decreases the incidence of nausea and vomiting	Low
9	Rasheed MA et al. [26]	2019	India	26	120	RCT,	Evaluation of Efficacy of Metoclopramide, Dexamethasone and Their Combination for the Prevention of Postoperative Nausea and Vomiting (PONV) in Patients Undergoing Cesarean Section.	Prophylactic administration of a combination of dexamethasone and metoclopramide was significantly superior for the prevention of PONV than the use of dexamethasone and metoclopramide alone.	Low
10	Modir H et al. [27]	2019	Iran	26	140	RCT,	Prophylactic efficacy of dexamethasone, ketamine, and Dexmedetomidine against intra-and postoperative nausea and vomiting under spinal anesthesia.	Dexmedetomidine has a greater effect in reducing nausea and vomiting. Although All three medications could reduce nausea and vomiting in patients. low	Low
11	Endalew ES et al. [28]	2018	Ethiopia	>	132	Prospective non-controlled,	Effectiveness of intravenous metoclopramide prophylaxis on the reduction of intraoperative and early postoperative nausea and vomiting after emergency cesarean section under spinal anesthesia.	metoclopramide Prophylaxis reduces the incidence and severity of intraoperative and early PONV compared to the non-treatment group	Low
12	Patel PC. et al. [29]	2021	India	30	90	Cross-sectional	Comparison of injection granisetron versus injection ondansetron for control of IONV and PONV among the women undergoing lower segment cesarean section under spinal anesthesia.	2 mg IV Granisetron is better in preventing intraoperative as well as PONV as compared to 4 mg IV ondansetron.	Low
13	Dasgupta M et al. [30]	2012	India	28.5	80	RCT,	Randomized, placebo-controlled trial of granisetron for control of nausea and vomiting during cesarean delivery under spinal anesthesia.	use of granisetron Prophylaxis is effective for preventing vomiting episodes during spinal anesthesia for cesarean section	Low
14	Chattopadhyay S et al. [31]	2015	Indian	26.5	109	RCT,	Palonosetron versus ramosetron prophylaxis for control of postoperative nausea and vomiting after cesarean delivery under spinal anesthesia.	Polanosetron Prophylaxis is more effective than ramosetron prophylaxis for the long-term prevention of PONV after cesarean section.	Low
15	Kampo S et al. [32],	2019	Ghana	30	345	RCT	Sub-hypnotic dose of Propofol as antiemetic prophylaxis attenuates intrathecal morphine-induced postoperative nausea and vomiting, and pruritus in parturient undergoing cesarean section	sub-hypnotic dose of Propofol has the same effectiveness as metoclopramide in the prevention of PONV in women undergoing cesarean section under spinal anesthesia with adjunct intrathecal morphine	Low
16	Abdalla E et al. [33]	2019	Egypt		120	RCT	Intravenous dexamethasone combined with intrathecal atropine to prevent morphine-related nausea and vomiting after cesarean delivery.	Combination of IV dexamethasone and intrathecal atropine has additive antiemetic effect after SA for CS using bupivacaine and morphine	low
17	Jabalameli M et al. [8]	2012	Iran	31.5	132	RCT	Treatment of postoperative nausea and vomiting after spinal anesthesia for cesarean delivery: comparison of midazolam, ondansetron, and a combination.	IV 30 μg/kg midazolam in combination with IV 8 mg ondansetron was superior to administering a single drug for the treatment of emetic symptoms after CS under SA.	Low