Table 5.

Meta‐analysis of relationship between SMI and domains of HRQOL: summary of findings

Domain	Study	Standardized mean difference between low and normal skeletal muscle mass
Social functioning	Five studies 42 , 44 , 45 , 48 , 49	n = 507, −0.06, 95% CI −0.24, 0.12, P = 0.53, I 2 0%
Role functioning	Four studies 42 , 45 , 48 , 49	n = 451, −0.25, 95% CI −0.63, 0.13, P = 0.20, I 2 67%
Emotional functioning	Three studies 42 , 45 , 48	n = 359, −0.11, 95% CI −0.33, 0.10, P = 0.29, I 2 0%
Cognitive functioning	Three studies 42 , 45 , 48	n = 359, −0.07, 95% CI −0.28, 0.15, P = 0.54, I 2 0%

CI, confidence interval; HRQOL, health‐related quality of life; SMI, skeletal muscle index.