Figure 3.

P7C3 enhances physical performance of db/db mice. (A) Fore‐limb grip strength and (B) hind‐limb grip strength measured and expressed as KGF/kg body weight. (C) The absolute force frequency and (D) normalized force frequency of the extensor digitorum longus muscles. (E) The area under the curve of the absolute muscle force frequency and (F) the normalized muscle force frequency. (G) The voluntary running wheel performance of the mice expressed in metres. Data are expressed as mean ± SEM; *P < 0.05; P7C3 vs. vehicle‐treated db/db mice. The age‐matched WT mice were used as naïve control to determine the baseline muscle force frequencies of the extensor digitorum longus muscle.