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. 2022 Feb 22;13(2):1164–1176. doi: 10.1002/jcsm.12949

Figure 4.

Figure 4

rIL‐6 treatment combined with moderate‐intensity low‐volume endurance training improves muscle fatigue resistance in situ. (A) Average curves showing the force decline during a 4‐min in situ muscle fatigue protocol on the M. tibialis anterior and of muscle force recovery up to 3 min after fatigue with (B) area under the curves corresponding to the force decline during muscle fatigue (Sed+Saline, n = 14; Sed+IL‐6, n = 15; Ex+Saline, n = 12; Ex+IL‐6, n = 14; and young Sed, n = 9). One‐way ANOVA followed by Sidak's multiple comparisons (B). *P < 0.05 and **P < 0.01 as indicated. ## P < 0.01 old groups vs. Young Sed group.