Table 1.
Baseline characteristics
| Pooled data | |
|---|---|
| n = 50 | |
| Event leading to ICU admission | |
| ARDS/sepsis | 30 (60%) |
| Polytrauma | 13 (26%) |
| Neurological/others | 7 (14%) |
| Sex | |
| Male | 36 (72%) |
| Female | 14 (28%) |
| Age (years) | 58.5 (42/68) |
| Weight (kg) | 81.5 (75/95) |
| Height (m) | 1.75 (1.7/1.8) |
| Illness severity scoring at ICU admission | |
| SOFA | 13 (10/14) |
| SAPS2 | 50.5 (39/63) |
| APACHE II | 23 (18/28) |
| ICU admission to HE clamp | |
| ICU stay (days) | 17 (15/21) |
| Fraction of these days with septic shock (%) | 20 (10/50) |
| Norepinephrine a (μg/kg/min) | 0.01 (0.001/0.067) |
| SOFA a | 9.9 (8.4/12.1) |
| Fraction of these days receiving insulin (%) | 92 (63/100) |
| Insulin a (IU/days) | 43.1 (26.4/64.2) |
| Blood glucose level (mg/dL) | 132.1 (124.9/138.9) |
| Caloric intake a (kcal/kg PBW/day) | 19.1 (15.2/22) |
| RASS score | −2.5 (−3.4/−1.8) |
ARDS, acute respiratory distress syndrome; HE, hyperinsulinaemic euglycaemic; ICU, intensive care unit.
Table showing baseline characteristics of pooled data; categorical variables are presented as count (percentage); metric variables are presented as median (25th/75th percentile); shown baseline characteristics show no significant differences between observational and interventional trials (Table S1).
a
Mean before HE clamp.